一、中心简介
首都医学科学创新中心（简称创新中心）是北京市新成立的具有独立法人资格的新型研发机构。创新中心以推动医学科学发展、改善人类健康为目标，开展生物医学研究，致力于提升医学科学创新与成果转化能力，提高疾病诊断和治疗水平。我们将汇聚世界高水平科学家，与首都医学教育和科学研究优质资源紧密合作，打造多学科交叉融合的科研平台，综合自由探索、医学目标导向、有组织科研等途径，实践新型科研模式和体制机制，逐步推进医教研产的深度融合，培养适应医学科学创新发展的优秀人才。
二、实验室介绍
首都医学科学创新中心免疫研究所孙少聪实验室招聘博士后或副研究员以开展癌症免疫和自身免疫的基础和转化研究。本实验室长期致力于T细胞的功能和机制研究。使用信号转导，CRISPR基因筛选，单细胞RNA测序，和基因敲除小鼠等多种方法研究T细胞激活，分化，效应功能和耗竭的分子机理，从而鉴定关键性T细胞调节因子。近期工作还包括运用生物信息学手段分析癌症患者肿瘤测序数据库，鉴定癌症免疫调节因子，然后用小鼠模型进行机理研究。自身免疫研究包括多发行硬化症，SLE，和肠炎的小鼠模型。
三、代表性论文
Nature Cell Biology 24: 1165-1176, 2022, PMID: 35773432
Nature Immunology 22: 193-204, 2021, PMID: 33398181
Nature Cell Biology 21: 1604-1614, 2019, PMID: 31792381
Nature Immunology 20: 879-889, 2019, PMID: 31182807
Nature Immunology 19: 1224-1235, 2018, PMID: 30250187
Nature 545: 365-369, 2017, PMID: 28489822
Nature Immunology 17: 259-268, 2016, PMID: 26808229
Nature Immunology 15: 562-570, 2014, PMID: 24777531
Immunity 40: 692-705, 2014, PMID: 24792914
Nature Medicine 19: 595-602, 2013, PMID: 23603814
Nature 494: 371-374, 2013, PMID: 23334419
四、博士后/副研究员
01、岗位职责
1.独立开展和参与实验室课题研究工作；
2.协助PI指导研究生工作。
02、任职要求
1.具有免疫学相关领域研究背景，即将或已经获得博士学位；副研究员需要有博士后研究经历；
2.具备独立开展科研工作和指导研究生能力，具有科研热情和严谨的科研态度；
3.具备熟练的英文交流和读写能力，可以独立撰写英文论文；
4.有扎实的免疫学、信息生物学、小鼠肿瘤免疫或自身免疫模型试验背景者优先考虑。
五、福利待遇
1.根据应聘者的工作经验和能力，提供具有市场竞争力的薪酬（详情面谈）；
2.享受五险一金、带薪年假、体检和补充医疗保险等；
3.支持个人职业发展，提供必要的工作相关专业培训。
六、申请方法
应聘者请将个人简历、研究兴趣或计划，以及2-3名推荐人的姓名及联系方式，以及其他能证明科研能力的相关电子文件发送到邮箱 ssun@cimrbj.ac.cn，邮件主题请注明“应聘者名字+具体应聘职位”。
联系人：
联系地址：北京市丰台区右安门外西头条10号-首都医学科学创新中心
本招聘长期有效，至招聘到合适人选为止。
ABOUT CIMR
Chinese Institutes for Medical Research (CIMR) is a newly founded institution dedicated to fundamental and translational medical research.The CIMR is located at the main campus of the
Laboratory Introduction
The laboratory of Shao-Cong Sun at the Chinese Institutes for Medical Research (CIMR) is recruiting motivated Postdoctoral Fellows and Research Associate Investigators to conduct basic and translational research in Cancer Immunology and Autoimmunity.A major focus of the lab is to study the molecular mechanisms that regulate T cell activation, differentiation, effector function, and exhaustion using a variety of cutting-edge techniques, such as signal transduction, CRISPR library screening, single-cell RNA sequencing, and knockout mouse models.Our recent work also includes the use of bioinformatics to analyze tumor sequencing databases of cancer patients, identify cancer immunomodulators, and then conduct mechanistic studies using mouse models.Autoimmune studies include mouse models of multiple sclerosis, SLE, and colitis.Professor Sun's team has made many significant contributions in this field, including the discovery of key factors regulating T cell functions in autoimmunity and cancer immunity.Our work also has strong translational potential and plays an important guiding role in drug development and disease treatment.The laboratory also uses mouse models of cancer immunotherapy to conduct translational studies and explore improved methods of immunotherapy.
Representative Publications
Nature Cell Biology 24: 1165-1176, 2022, PMID: 35773432
Nature Immunology 22: 193-204, 2021, PMID: 33398181
Nature Cell Biology 21: 1604-1614, 2019, PMID: 31792381
Nature Immunology 20: 879-889, 2019, PMID: 31182807
Nature Immunology 19: 1224-1235, 2018, PMID: 30250187
Nature 545: 365-369, 2017, PMID: 28489822
Nature Immunology 17: 259-268, 2016, PMID: 26808229
Nature Immunology 15: 562-570, 2014, PMID: 24777531
Immunity 40: 692-705, 2014, PMID: 24792914
Nature Medicine 19: 595-602, 2013, PMID: 23603814
Nature 494: 371-374, 2013, PMID: 23334419
Open Positions
Postdoctoral Fellows /
Research Associate Investigators
Main Responsibilities
a.Carrying out research projects independently.
b.Assisting PI to mentor graduate student.
Qualifications
a.With research background in immunology related biomedical fields, either about to obtain or having already obtained a doctoral degree; postdoctoral experience is required for research associate investigator position.
b.With motivation and ability to independently carry out research projects and supervise graduate students, and have strong motivation in scientific research.
c.Proficient in English reading, writing, and daily communication; capable of writing papers in English.
d.Those with solid background in immunology, bioinformatics, mouse models of cancer immunity or autoimmunity, or CRISPR screen will be given priority.
Welfare Treatment
a.Provide competitive salary based on the applicant’s work experience and ability (salary negotiable).
b.Provide social insurance and housing fund, supplementary medical insurance, physical examination and paid annual leave.
c.Support career development, provide relevant professional guidance.
How to apply
To apply, please send personal resume, research interest or plan, the names and contacts of 2-3 referees and other materials demonstrating research capabilities to ssun@cimrbj.ac.cn, and indicate the applicant's name and specific job position in the email subject.
Contact person: Dr.Sun
This recruitment is valid for the long term until a suitable candidate is recruited.
信息来源于网络，如有变更请以原发布者为准。
来源链接：
https://mp.weixin.qq.com/s/826vE_T8fw2KtdqX0VhpQQ
